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What stimulates prolactin release? In addition to tonic inhibition by dopamine, prolactin secretion is positively regulated by several hormones, including thyroid- releasing hormone, gonadotropin- releasing hormone and vasoactive intestinal polypeptide. Stimulation of the nipples and mammary gland, as occurs during nursing, leads to prolactin release.
Do pituitary tumors show up on MRI? A normal pituitary gland will usually look very white on a MRI after the dye has been used. The tumors will appear darker. This pattern is different than it is for other tumors. Dynamic MRIs may be especially important when a small tumor of the type that causes acromegaly or Cushing's disease is suspected.
Can prolactin make you gain weight? CONCLUSION: Weight gain and elevated body weight are frequently associated with prolactinomas regardless of a mass effect on the hypothalamus or pituitary function. In this series, weight loss was recorded in 70% of prolactinomas patients and in 90% of male patients who normalized their prolactin levels.
Do pituitary tumors come back? That is because some noncancerous pituitary gland tumors do not grow back even when some of the tumor is left behind after surgery. If the entire tumor is removed, then radiation therapy is not needed. It can also cause the pituitary gland to gradually lose the ability to make hormones after treatment ends.
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